Brupal/Brupal Forte/Brupal Kid Adverse Reactions

Ibuprofen: Cardiovascular System: Tachycardia, flushing, increase in blood pressure.
Central Nervous System: Confusion, hallucinations, mental depression, peripheral neuropathy, tinnitus, drowsiness, insomnia.
Gastrointestinal System: Epigastric pain or discomfort, gastritis, hematemesis, GI perforation, GI ulceration.
Dermatological: Allergic dermatitis, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis.
Renal: Hematuria, cystitis, renal impairment or failure, polyuria, fluid retention/oedema, acute renal failure, interstitial nephritis, nephrotic syndrome.
Hematological: Agranulocytosis, anaemia, aplastic anaemia, eosinophilia, hemolytic anaemia, leukopenia, thrombocytopenia.
Hypersensitivity Reactions: Anginitis, angioedema, bronchospastic allergic reactions, allergic rhinitis, serum sickness-like reaction, systemic lupus erythematosus, aseptic meningitis.
Ophthalmic: Amblyopia, blurred or double vision, conjunctivitis, dry irritated or swollen eyes, scotoma.
Oral: Aphthous stomatitis, gingival ulcerations.
Ear, Nose and Throat: Decreased hearing or any change in hearing, epistaxis.
Hepatic Effect: Hepatitis.
Pancreatic Effect: Pancreatitis.
Paracetamol: Gastrointestinal System: Nausea, vomiting, stomach pain or cramps, diarrhoea, loss of appetite, hepatotoxicity, hepatic failure, hepatic encephalopathy, GIT bleeding, pancreatitis.
Central Nervous System: Convulsions, respiratory depression, cerebral oedema, coma.
Haematological: Leucopenia, thrombocytopenia, neutropenia, pancytopenia, agranulocytosis, disseminated intravascular coagulation.
Metabolic: Hypoglycaemia, metabolic acidosis.
Cardiovascular System: Cardiac arrhythmias, cardiovascular collapse.
Renal System: Renal tubular necrosis, renal failure.
Dermatological: Skin rashes and other allergic reactions. The rash is usually erythematous or urticarial but sometimes more serious and may be accompanied by fever and mucosal lesions.